Biomolecular Interactions & Biophysics
Barnham lab and NSV Proteomics Service, University of Melbourne
We can help with a variety of biophysical approaches for characterising proteins, peptides and biomolecular interactions, including circular dichroism spectroscopy, fluorescence spectroscopy and biosensor technology. We also use organic chemistry to produce small ligands.
Please contact:
Kevin Barnham
Email: kbarnham@unimelb.edu.au
Phone: + 61 3 8344 2555
We can assist with the application of sensor platform technology to resolve the binding specificity, kinetic parameters and affinity associated with molecular interactions (protein-protein, protein-small molecule).
Work is accepted from academic and commercial clients.
Please contact:
Olan Dolezal, Facility Manager
Email: Olan.Dolezal@csiro.au
Phone: +61 3 9662 7229
Meghan Hattarki
Email: Meghan.Hattarki@csiro.au
Phone: +61 3 9662 7243
Hatters lab, University of Melbourne
We can assist with the design and implementation of fluorescence approaches to investigate protein conformational changes directly in live cells using confocal microscopy. We also investigate protein-protein complexes and heterogeneity using analytical ultracentrifugation.
Please contact:
Danny Hatters
Email: dhatters@unimelb.edu.au
Phone: +61 3 8344 2530
Perugini lab & Macromolecular Interactions Facility, University of Melbourne
We can help with a variety of biophysical approaches for determining native molecular mass, shape, structure and interactions of biomolecules in solution, including analytical ultracentrifugation, circular dichroism spectroscopy and fluorescence spectroscopy.
Please contact:
Matt Perugini (Lab Head & Facility Manager)
Email: perugini@unimelb.edu.au
Phone: + 61 3 8344 2355
Mulhern lab, University of Melbourne
Nice lab, Ludwig Institute and Monash University
Crystallography
Parker lab, St Vincent's Institute
We can help with a broad range of biophysical studies of proteins. Key platform technologies include X-ray crystallography, molecular modelling, protein expression and engineering, protein purification, circular dichroism, dynamic light scattering, electrophysiology, structure-based drug design including virtual and fragment screening. Please contact:
Michael Parker
Email: mparker@svi.edu.au
Phone: + 61 3 9288 2499
Bio21 Collaborative Crystallisation Centre, CSIRO
Colman lab, WEHI
White lab, Bio21
Rossjohn lab & Protein Crystallography Unit, Monash University
We can assist broadly with protein crystallography. Key infrastructure covers protein crystallization (robotized), X-ray diffraction, molecular modelling, recombinant protein expression (prokaryote, eukaryote), protein purification, Biacore analysis and isothermal calorimetry.
Please contact:
Jamie Rossjohn
Email: jamie.rossjohn@med.monash.edu.au
Phone: +61 3 9902 9236
Whisstock lab, Monash University
Matthew Wilce lab, Monash University
Buckle lab, Monash University
NMR
Barnham lab & NSV Proteomics Service, University of Melbourne
We can help with NMR analysis of small molecules and peptides.
Please contact:
Kevin Barnham
Email: kbarnham@unimelb.edu.au
Phone: + 61 3 8344 2555
Gooley lab, University of Melbourne
We can assist with NMR analysis of proteins and peptides, with particular experience in dynamical analyses and protein interactions. We can also help with large scale protein purification and are interested in applying NMR methods to metabolomics.
Please contact:
Paul Gooley
Email: prg@unimelb.edu.au
Phone: + 61 3 8344 2273
Norton lab, WEHI
We can help with NMR analysis of protein structure, function and dynamics, structure-based molecular design. We can also assist with protein purification and characterization using a wide range of structural and biophysical methods.
Please contact:
Raymond Norton
Email: ray.norton@wehi.edu.au
Phone: +61 3 9345 2306
Hinds lab, WEHI
We can assist with many aspects of protein structure determination. We are expert in the use of nuclear magnetic resonance (NMR) spectroscopy to investigate protein and peptide structures and interactions in solution.
Please contact:
Mark Hinds
Email: mhinds@wehi.edu.au
Phone: +61 3 9345 2537
Separovic lab, University of Melbourne
We can help with determining the structure of membrane-active peptides using solid-state NMR techniques primarily.
Please contact:
Frances Separovic
Email: fs@unimelb.edu.au
Phone: +61 3 8344 2447
Bio21 NMR Facility, University of Melbourne
Jackie Wilce lab, Monash University
Martin Stone lab, Monash University